山西大学
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教授

张昕

|作者: 董秀清 |日期：2024-03-31 |访问量：

张昕，现任职山西大学环境科学研究所，三级教授，博士生导师，山西大学科学研究伦理审查委员会副主任，山西省“三晋英才”，山西省高校优秀青年学术带头人，曾任中国环境科学学会—室内环境与健康分会青委会副主任、工业环境与健康学组副组长。2009年获得山西大学生化与分子生物学博士学位，2010年赴瑞典乌普萨拉大学完成二年博士后工作，2014-2015年在加拿大UBC大学访问。近年来在Environ.Sci.Technol., Free Radical Bio. Me., Environ. Int., Sci. Total Environ., Microbiome. Indoor Air等国内外期刊发表学术论文81篇，主持国家级国际合作基金1项，国家自然科学基金3项，省市基金多项。曾获得山西省科学技术二等奖2项（排名第一、第二），中国环境科学学会青年科技奖，山西省三八红旗手等多项奖励，为山西大学2009年度优秀引进人才，山西大学2019年度“十佳青年教师”。

研究方向：1.学校空气污染与儿童呼吸道疾病的暴露-效应关系；2.焦化行业颗粒物、有机化合物等毒害污染物的暴露组学与生物标志物；3.室内微生物（组）与人体健康的交互作用。

主讲课程： 环境学概论（本科生）

联系方式：0351-7011011   E-mail: xinzhang0051@sxu.edu.cn

主持科研项目（课题）情况:

1. 国家自然科学基金面上项目，42177419，焦化工业园区大气细颗粒物及所含毒害污染物对周边儿童健康的影响，2022/01-2025/12，57万元，主持

2. 大金（中国）投资有限公司深圳研发分公司委托项目，空气净化器干预对在校学生呼吸道健康效应的影响研究，2021/12-2025/03，85万元，主持

3. 大金（中国）投资有限公司深圳研发分公司委托项目，空气采样机的螨虫采样及螨虫过敏原分析方法的研究开发，2020/12-2023/03，35万元，主持

4. 国家自然科学基金地区合作项目，81861138005，室外大气污染与室内环境因素对儿童“哮喘-鼻炎-湿疹”等相关疾病健康效应的多城市研究，2018/01-2021/12，60万元，主持

5. 山西省重点研发计划，201803D31021，不同来源大气颗粒物与学生哮喘-过敏-湿疹队列研究，2018/12-2020/12，10万元，主持

6. 太原市恩兆因公司委托项目，太原市环境污染与健康研究，2015/01-2017/12，25.4万元，主持

7. 山西省优秀青年学术带头人，2014/01-2014/12，10万元，主持

8. 国家自然科学基金青年基金项目，21207083，煤烟型污染城市学校室内外空气细颗粒物化学成分及与儿童呼吸道健康的暴露－效应研究，2013/01-2015/12，25万元，主持

9. 太原市环保局环境科学技术研究项目，201301，城区学校大气环境与学生呼吸道健康影响研究，2013/01-2015/12，15万元，主持

10. 中瑞国际合作项目，348-2011-7402，Indoor and outdoor environmental pollution, diet and aspects of food safety in China: Health studies in school children in different parts of China，2012/01-2014/12，35万瑞典克朗，主持

发表论文（通讯作者*）：

1. Yang L, Gao H, Wang Y, Norbäck D, Zhao Z, Fu X, Sun Y, Zhang X*. 2025. Environmental impacts on childhood rhinitis: The role of green spaces, air pollutants, and indoor microbial communities in Taiyuan, a city in Northern China. Ecotoxicol Environ Saf. 289:117662. https://doi.org/10.1016/j.ecoenv.2024.117662

2. Yang L, Chen H, Gao H, Wang Y, Chen T, Svartengren M, Norbäck D, Wei J, Zheng X, Zhang L, Lu C, Yu W, Wang T, Ji JS, Meng X, Zhao Z, Zhang X*. 2024. Prenatal and postnatal early life exposure to greenness and particulate matter of different size fractions in relation to childhood rhinitis - A multi-center study in China. Sci Total Environ. 938:173402. https://doi.org/10.1016/j.scitotenv.2024.173402

3. Cheng H, Wang S, Shao J, Gao H, Wang Y, Deng F, Du H, Liu J, Du X, Zhang X*. 2024. Associations of Ozone Exposure with Serum Biomarkers in Acute Myocardial Infarction Patients in Taiyuan, China: The Mediating Role of Metabolites. Environ Health. 3(1):79-90. https://doi.org/10.1021/envhealth.4c00122

4. Hong Cheng, Xingyi Chen, Huilin Zhang, Liu Yang, Shengchun Wang, Zhuohui Zhao, Dan Norbäck & Xin Zhang*. 2024. Elemental composition and health risks of indoor PM2.5 in Taiyuan, China: Associations with fractional exhaled nitric oxide (FeNO) in preschoolers, Human and Ecological Risk Assessment: An International Journal, https://doi.org/10.1080/10807039.2024.2436667

5. Cheng H, Norbäck D, Zhang H, Yang L, Li B, Zhang Y, Zhao Z, Deng, Q, Huang C, Yang X, Lu C, Qian H, Wang T, Zhang L, Yu W, Wang J, Zhang X*. 2024. Home environment exposure and sick building syndrome (SBS) symptoms among adults in southern China: Health associations in 2010 and 2019. Build Environ. 248. https://doi.org/10.1016/j.buildenv.2023.111061

6. Shao J, Fu P, Wang S, Cheng H, Zhang X*. 2024. Occupational exposure to silica and risk of gastrointestinal cancers: a systematic review and meta-analysis of cohort studies. Int Arch Occup Environ Health. 97(3):231-251. https://doi.org/10.1007/s00420-024-02045-3

7. Li H, Zhang S, Yao C, He R, Lu P, Li G, Liu R, Ma S, Zhang X, Cao Z, An T. 2023. Nontarget Screening of Novel Urinary Biomarkers for Occupational Exposure to Toxic Chemicals from Coking Industry Using HPLC-QTOF-MS. Environ Sci Technol. 57(35):13004-13014. https://doi.org/10.1021/acs.est.3c01663

8. Li H, Yao C, He C, Yu H, Yue C, Zhang S, Li G, Ma S, Zhang X, Cao Z, An T. 2023. Coking-Produced Aromatic Compounds in Urine of Exposed and Nonexposed Populations: Exposure Levels, Source Identification, and Model-Based Health Implications. Environ Sci Technol. 57(41):15379-15391. https://doi.org/10.1021/acs.est.3c04906

9. Yang L, Yang Z, Zhao Z, Norbäck D, Cai YS, Zhang X*. 2023. Exposure to greenness, air pollution and respiratory health among pre-school children in northern China. Atmos Environ. 298. https://doi.org/10.1016/j.atmosenv.2023.119608

10. Zhang B, Norbäck D, Cheng H, Li B, Zhang Y, Zhao Z, Deng Q, Huang C, Yang X, Lu C, Qian H, Wang T, Zhang L, Yu W, Wang J, Zhang X*. 2023. Dampness and mould in Chinese homes and sick building syndrome (SBS) symptoms – Associations with climate, family size, cleaning and ventilation. Build Environ. 245. https://doi.org/10.1016/j.buildenv.2023.110878

11. Wang S, Niu Y, Zhang H, Zhao Z, Zhang X*. 2023. Metabolomic alterations in healthy adults traveling to low-pollution areas: A natural experiment with ozone exposure. Sci Total Environ. 897, 165501. https://doi.org/10.1016/j.scitotenv.2023.165501

12. Zhang H, Liu R, Yang L, Cheng H, Wang S, Zhang B, Shao J, Ma S, Norbäck D, Zhang X*, An T. 2023. Exposure to polycyclic aromatic hydrocarbons (PAHs) in outdoor air and respiratory health, inflammation and oxidative stress biomarkers: A panel study in healthy young adults. Sci Total Environ. 899. https://doi.org/10.1016/j.scitotenv.2023.165582

13. Zhang Z, Zhang H, Yang L, Chen X, Norbäck D, Zhang X*. 2022. Associations between outdoor air pollution, ambient temperature and fraction of exhaled nitric oxide (FeNO) in university students in northern China - A panel study. Environ Res. 212. https://doi.org/10.1016/j.envres.2022.113379

14. Sun Y, Meng Y, Ou Z, Li Y, Zhang M, Chen Y, Zhang Z, Chen X, Mu P, Norbäck D, Zhao Z, Zhang X*, Fu X. 2022. Indoor microbiome, air pollutants and asthma, rhinitis and eczema in preschool children – A repeated cross-sectional study. Environ Int. 161. https://doi.org/10.1016/j.envint.2022.107137

15. Fu X, Li, Y, Meng Y, Yuan Q, Zhang Z, Wen H, Deng Y, Norbäck D, Hu Q, Zhang X*, Sun Y. 2021. Derived habitats of indoor microbes are associated with asthma symptoms in Chinese university dormitories. Environ Res. 194. https://doi.org/10.1016/j.envres.2020.110501

16. Fu X, Ou Z, Zhang M, Meng Y, Li Y, Wen J, Hu Q, Zhang X, Norbäck D, Deng Y, Zhao Z, Sun Y. 2021. Indoor bacterial, fungal and viral species and functional genes in urban and rural schools in Shanxi Province, China-association with asthma, rhinitis and rhinoconjunctivitis in high school students. Microbiome. https://doi.org/10.1186/s40168-021-01091-0

17. Norbäc D, Zhang X*, Tian L, Zhang Y, Zhang Z, Yang L, Chen X, Zeng Z, Lu C, Zhao Z. 2021. Prenatal and perinatal home environment and reported onset of wheeze, rhinitis and eczema symptoms in preschool children in Northern China. Sci Total Environ. 774, 145700. https://doi.org/10.1016/j.scitotenv.2021.145700

18. Fu X, Li Y, Meng Y, Yuan Q, Zhang Z, Norbäck D, Deng Y, Zhang X*, Sun Y. 2020. Associations between respiratory infections and bacterial microbiome in student dormitories in Northern China. Indoor Air 30, 816–826. https://doi.org/10.1111/ina.12677

19. Li T, Zhang X*, Li C, Bai X, Zhao Z, Norback D. 2020. Onset of respiratory symptoms among Chinese students: associations with dampness and redecoration, PM10, NO2, SO2 and inadequate ventilation in the school. J Asthma 57, 495–504. https://doi.org/10.1080/02770903.2019.1590591

20. Zhang X, Bai X, Li C, Li T, Wang R, Zhao Z, Norback D. 2020. Elemental composition of ambient air particles in Taiyuan, China: evaluation of lifetime cancer and non-cancer risks. Hum Ecol Risk Assess. 26, 1391–1406. https://doi.org/10.1080/10807039.2019.1579048

21. Norbäck D, Zhang X*, Fan Q, Zhang Z, Zhang Y, Li B, Zhao Z, Huang C, Deng Q, Lu C, Qian H, Yang X, Sun Y, Sundell J, Wang J. 2019. Home environment and health: Domestic risk factors for rhinitis, throat symptoms and non-respiratory symptoms among adults across China. Sci Total Environ. 681, 320–330. https://doi.org/10.1016/j.scitotenv.2019.05.084

22. Zhang X, Norbäck D, Fan Q, Bai X, Li T, Zhang Y, Li B, Zhao Z, Huang C, Deng Q, Lu C, Qian H, Xu Y, Sun Y, Sundell J, Wang J. 2019. Dampness and mold in homes across China: Associations with rhinitis, ocular, throat and dermal symptoms, headache and fatigue among adults. Indoor Air 29, 30–42. https://doi.org/10.1111/ina.12517

23. Norback D, Li T, Bai X, Li C, Zhao Z, Zhang X*. 2019. Onset and remission of rhinitis among students in relation to the home and school environment—A cohort study from Northern China. Indoor Air 29, 527–538. https://doi.org/10.1111/ina.12559

24. 杨柳, 赵卓慧, Dan, N, 张昕*. 2023. 生命早期空气污染物与绿地暴露对太原市学龄前儿童特应性疾病的影响 13, 1–8.

25. 王晟春, 张泽斐, Dan, N, 张昕*. 2022. 太原市环境空气污染对大学生呼出气一氧化氮的影响 —— 定群研究 45, 1665–1674.

社会服务：长期为全球知名、世界500强企业进行产品调研和服务；与太原市教育局、市疾控中心等卫生环保部门建立了良好的合作关系；每年不定期在小学、幼儿园进行环境保护知识宣传和健康普查。

专利和获奖情况：

(1) 张昕(1/4)；学校室内空气污染与健康风险及控制对策研究，山西省科技厅，科学技术奖二等奖，2021（张昕；耿红；Dan Norback；Gunilla Wieslander）.

(2) 张昕(1/1)；山西省“三晋英才”支持计划青年优秀人才，中共山西省委，2019.

(3) 张昕(2/6)；特异性过敏原的重组制备及过敏与哮喘的检测，山西省科技厅，科学技术奖二等奖，2014（王转花；张昕；崔晓东；李玉英；赵卓慧；李晨）.

(4) 张昕；张丽；李凡；检测哮喘易感基因ADRB2突变位点的探针和方法，2014，中国，CN201410262409.0.

(5) 张昕(1/1)；中国环境科学学会青年科技奖，中国环境科学学会，2014.

(6) 张昕(1/1)；山西省高校优秀青年学术带头人，山西省教育厅，2014.